Tuesday, April 18, 2017

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Saturday, April 8, 2017

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Thursday, March 30, 2017

How Do Systemic Enzymes Work



 

How Systemic Enzymes Work


 What do the enzymes do if they aren’t digesting your food?

When you take enzymes, specifically protease or proteolytic enzymes, on an empty stomach, instead of the protease helping to digest the protein from your meal, the enzymes will enter your bloodstream to support the circulatory system, the immune system and work to support overall detoxification. The better the blood flow and the healthier your circulatory system, the better the detoxification. This type of enzyme use is called “systemic enzyme supplementation.” The use of systemic enzymes is great for healthy individuals, but can provide additional support for those with compromised immune systems.

Some conditions that may be exacerbated by undigested proteins and food particles in your body are leaky gut, arthritis, fibromyalgia, CFS, allergies, to name just a few.




Wednesday, March 29, 2017

What Are Systemic Enzymes and What Do They Do?

What Are Systemic Enzymes and What Do They Do?
By: Dr. William Wong ND, PhD



The word “systemic” means body wide. Systemic enzymes are those that operate not just for digestion but throughout your body in every system and organ. But let’s take first things first, what is an enzyme?
An enzyme is a biocatalyst - something that makes something else work or work faster. Chemical reactions are generally slow things, enzymes speed them up. Without enzymes the chemical reactions that make up our life would be too slow for life as we know it. (As slow as sap running down a tree in winter). For life to manifest as we know it, enzymes are essential to speed up the reactions. We have roughly some 3000 enzymes in our bodies and that results in over 7000 enzymic reactions. Most of these enzymes are derived or created from what we think of as the protein digesting enzymes. But while digestion is an important part of what enzymes do, it's almost the absolute last function. First and foremost these body wide proteolytic (protein eating) enzymes have the following actions:
Natural Anti-Inflammatory.
They are the first line of defense against inflammation. (1,2,3). Inflammation is a reaction by the immune system to an irritation. Let’s say you have an injured right knee. The immune system sensing the irritation the knee is undergoing creates a protein chain called a Circulating Immune Complex (CIC for short), tagged specifically for that right knee. (The Nobel Prize in biology was won in 1999 by a scientist who discovered this tagging mechanism). This CIC floats down to the right knee and causes pain, redness and swelling are the classic earmarks for inflammation. This at first is a beneficial reaction; it warns us that a part of ourselves is hurt and needs attention. But, inflammation is self-perpetuating, itself creating an irritation that the body makes CIC’s to in response!

Aspirin, Ibuprofen, Celebrex, Vioxx and the rest of the Non Steroidal Anti Inflammatory Drugs all work by keeping the body from making all CIC's. This ignores the fact that some CIC’s are vital to life, like those that maintain the lining of the intestine and those that keep the kidneys functioning! Not to mention the fact that the NSAID’s, along with acetaminophen, are highly toxic to the liver. Every year 20,000 Americans die from these over the counter drugs and another 100,000 will wind up in the hospital with liver damage, kidney damage or bleeding intestines from the side effects of these drugs. (4,5).

Systemic enzymes on the other hand are perfectly safe and free of dangerous side effects. They have no LD-50, or toxic dose. (6). Best of all systemic enzymes can tell the difference between the good CIC’s and the bad ones because hydrolytic enzymes are lock and key mechanisms and their "teeth" will only fit over the bad CIC’s. So instead of preventing the creation of all CIC’s, systemic enzymes just “eat” the bad ones and in so doing lower inflammation everywhere. With that, pain is lowered also.

 

Anti Fibrosis.
Enzymes eat scar tissue and fibrosis. (7). Fibrosis is scar tissue and most doctors learn in anatomy that it is fibrosis that eventually kills us all. Let me explain. As we age, which starts at 27, we have a diminishing of the bodies’ output of enzymes. This is because we make a finite amount of enzymes in a lifetime and we use up a good deal of them by the time we are 27. At that point the body knows that if it keeps up that rate of consumption we’ll run out of enzymes and be dead by the time we reach our 40’s. (Cystic Fibrosis patients who have virtually no enzyme production to speak of, even as children usually don’t make it past their 20’s before they die of the restriction and shrinkage in the lungs from the formation of fibrosis or scar tissue).

So our body in it's wisdom begins to dole out our enzymes with an eyedropper instead of with a tablespoon; as a result the repair mechanism of the body goes out of balance and has nothing to reduce the over abundance of fibrin it deposits in nearly every thing from simple cuts, to the inside of our internal organs and blood vessels. This is when most women begin to develop things like fibrocystic breast disease, uterine fibroids, endometriosis, and we all grow arterial sclerotic (meaning scar tissue) plaque, and have fibrin beginning to spider web its way inside of our internal organs reducing their size and function over time. This is why as we age our wounds heal with thicker, less pliable, weaker and very visible scars.

If we replace the lost enzymes we can control and reduce the amount of scar tissue and fibrosis our bodies have. As physicians in the US are now discovering, even old scar tissue can be “eaten away” from surgical wounds, pulmonary fibrosis, kidney fibrosis and even keloids years after their formation. Medical doctors in Europe and Asia have known this and have used orally administered enzymes for these situations for over 40 years!

Blood Cleansing.
The blood is not only the river of life, it is also the river through which the cells and organs dispose of their garbage and dead material. Enzymes improve circulation by eating the excess fibrin that causes blood to sometimes get as thick as catsup or yogurt, creating the perfect environment for the formation of clots. All of this material is supposed to be cleared by the liver on its "first pass", or the first time it goes through but given the sluggish and near toxic or toxic states of everyone's liver these days that seldom happens. So the sludge remains in the blood waiting for the liver to have enough free working space and enough enzymes to clean the trash out of the blood. This can take days, and in some cases, weeks! (8).
When systemic enzymes are taken, they stand ready in the blood and take the strain off of the liver by:
  1. Cleaning excess fibrin from the blood and reducing the stickiness of blood cells. These two actions minimize the leading causes of stroke and heart attack causing blood clots. (8).
  2. Breaking dead material down small enough that it can immediately pass into the bowel. (8).
  3. Cleanse the FC receptors on the white blood cells improving their function and availability to fight off infection. (9).

And here we come to the only warning we have to give concerning the use of systemic enzymes - don't use the product if you are a hemophiliac or are on prescription blood thinners like Coumadin, Heparin and Plavix, without direct medical supervision. The enzymes cause the drugs to work better so there is the possibility of thinning the blood too much.

Immune System Modulating.
Enzymes are adaptogenic seeking to restore a steady state to the body. (9). When the immune system is running low we become susceptible to infectious disease, when it’s cranked up too high then the system creates antibodies that attack it's own tissues as are seen in the auto immune diseases of MS, Rheumatoid Arthritis, and Lupus. Here the enzymes will tone down immune function and eat away at the antibodies the immune system is making to attack its bodies own tissue.

Virus Fighting.
Viruses harm us by replicating in our bodies. To do this a virus must bond itself to the DNA in our cells through the medium of its exterior protein cell wall. Anything that disrupts that cell wall inhibits the ability of viral replication by rendering individual viruses inert. (10,11). Systemic enzymes can tell the difference between the proteins that are supposed to be in your body and those that are foreign or not supposed to be there, (again the enzyme lock and key mechanism).

One note: many in the States have learned in school that enzymes are too big a protein to be absorbed through the gut. The pioneering research done in the US by Dr. Max Wolf (MD & PhD x7) at Columbia University in the 40’s through the 70’s has not made it to the awareness of most doctors. There are currently over 200 peer reviewed research articles dealing with the absorption, utilization and therapeutic action of orally administered systemic enzymes. A search through Pub Med using the key words: serrapeptase, papain, bromelain, trypsin, chymo trypsin, nattokinase and systemic enzyme will yield some of the extensive work. Systemic enzymes now have a 4 decade plus history of widespread medical use in central Europe and Japan.

References: **

1) Carroll A., R.: Clinical examination of an enzymatic anti-inflammatory agent in emergency surgery. Arztl. Praxis 24 (1972), 2307.
2) Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic
inflammation of otorhinolaryngology pathology: a multicentre, double blind,
randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment of breast engorgement with Serrapeptase: a randomized double blind controlled trial. Singapore Med J. 1989:30(l):48-54.
4) Celebrex article Wall Street Journal 19 April 1999.
5) No author listed: Regular Use of Pain Relievers Can Have Dangerous Results. Kaleidoscope Interactive News, American Medical Association media briefing. July 24, 1997.
6) Enzymes ñ A Drug of the Future, Prof. Heinrich Wrba MD and Otto Pecher MD. Published 1993 Eco Med.
7) Kakinumu A. et al.: Regression of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.
8) Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology. Klin Wschr. 65 (1987), 994.
9) Kunze R., Ransberger K., et at: Humoral immunomodulatory capasity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991.
10) Jager H.: Hydrolytic Enzymes in the therapy of HIV disease. Zeitschr. Allgemeinmed., 19 (1990), 160.
11) Bartsch W.: The treatment of herpes zoster using proteolytic enzymes. Der Informierte Arzt. 2 (1974), 424-429.

Friday, March 24, 2017

Systemic enzymes CAN help with pain from fibroids




Systemic enzymes eliminate pain, fibroids and boost immunity

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How the human body reacts to chronic stress or injury

When the body is injured or under chronic stress the immune system initiates a protein chain called ‘Circulating Immune Complex’ (CIC) that causes pain, redness and swelling in a particular region. This is a beneficial process and early on is a necessary part of healing. However, inflammation is self-perpetuating and creates further insult and irritation to the region. Unless there is modulation of the CIC response the inflammation can dominate and overwhelm the region of the body creating painful and degenerative conditions.

Non-steriodal anti-inflammatory drugs (NSAID’s) work by blocking CIC activity in the body. This affects all CIC’s including those used to maintain the lining of the stomach, intestine, liver and kidneys. This is why long-term NSAID usage causes liver and kidney toxicity, stomach ulcers and leaky gut syndrome.

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Every year, 20,000 Americans die from the over counter use of these drugs and another 100,000 end up in the hospital with liver and kidney damage and intestinal bleeding from NSAID usage.

Systemic enzymes work to modulate or coordinate the activity of CIC’s and have no major adverse reactions. They work as a lock and key mechanism and have an affinity for pro-inflammatory cytokines such as ‘Tumor Necrosis Factor’ (TNF) and ‘C Reactive Protein’ (CRP).

Can systemic enzymes actually help us prevent disease?
Systemic enzymes help to destroy foreign proteins which include viruses, bacteria, yeasts and other parasites. They also help to destroy abnormal cells such as cancer cells. In addition, they will destroy excessive antibodies that the body is producing such as in cases of autoimmune diseases.

Do systemic enzymes create ‘anti-fibrolytic’ activity?
Yes! Fibrosis is scar tissue that the body produces in the repair process of cuts and wounds on the outer and inner surfaces of our body. When we have optimal enzyme stores – the enzymes are used to clean up fibrolytic tissue in the body. However, when our enzyme stores are being depleted due to chronic stress and inflammatory activity the fibrolytic tissue builds up.

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When the body has an abundance of fibrolytic tissue build up we end up with things like fibrocystic breast disease, uterine fibroids, endometrosis and arteriol sclerosis. Systemic enzymes eat fibrolytic tissue and prevent the fibrosis of our organs and tissues. They have a remarkable ability to not only prevent all of the above conditions but also to eat up old scar tissue. This includes surgical wounds, pulmonary fibrosis, kidney fibrosis and even old keloid plaques.


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How do systemic enzymes help to clean up the blood?
Chronically inflamed individuals often times end up with very thick blood that is loaded with fibrin that can lead to heart attacks and strokes. Doctors often prescribe aspirin and in more extreme cases powerful pharmaceuticals like Coumadin, Heparin and Plavix. And, of course, these drugs have very dangerous side effects.

Systemic enzymes are able to clear up excess thickening agents such as fibrin from the bloodstream and naturally thin the blood. They also break down dead material including dead blood cells, pathogens, toxic debris and immune agents that have been left in circulation. This helps cleanse and detoxify the bloodstream and enhances circulation and cellular oxygenation.

If you’re concerned about your health condition and want to use systemic enzymes (properly) – find a doctor with experience, in this area, to guide you in the right direction.

 

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Thursday, March 23, 2017

Excellacor Benefits




Health Benefits of Serrapeptase

Analgesic: Serrapeptase has been used for several years as an analgesic for inflamed tissues and general aches and pains. These effects are accomplished through the inhibition of pain-causing molecules called amines. When tissues are inflamed, blood vessels become dilated and chemical messengers are relayed to the brain to increase the sensation of pain. Serrapeptase works against discomfort by reducing the recruitment of these pain molecules to sites of inflammation, and allowing for reparative molecules to facilitate the healing process more rapidly. When pain is reduced, secondary factors like stress and mood are also improved.

Anti-inflammatory: Perhaps one of serrapeptase’s best-known properties, it has been used, and proven in various clinical studies to be effective in similar ways as NSAID anti-inflammatory agents. Serrapeptase is particularly effective on localized sites of inflammation, aiding in the clearing of cellular debris and encouraging the body’s natural ameliorative effects on edema. Serrapeptase is often compared to NSAID pain relievers, but it should be noted that serrapeptase as an oral systemic enzyme does not contain similar risks and side-effects to those of NSAID’s. Serrapeptase does not threaten the gastrointestinal lining, nor does it increase the risk for gastric ulcers. In fact, it is typical for clinical studies to note the impressive tolerability of serrapeptase as an oral therapy.

Mucolytic: Because serrapeptase has the ability to break down and digest protein waste, it has been studied in upper respiratory conditions, and has shown promising results. As a mucolytic, serrapeptase is capable in dramatically reducing sputum viscosity in human patients. This means that the serrapeptase thins the mucus, which allows for the patients to more readily expel mucus from the airway. Serrapeptase, therefore, is a promising agent in common conditions like chronic sinusitis, and ear, nose and throat conditions that are characterized by increased mucus production.

Healing injuries: Serrapeptase is a known supplement among professional athletes for both prevention and treatment of sports injuries. Injured joints, ligaments and muscles are coated with fibrin that supports the injured tissue as it heals. The body can sometimes produce too much fibrin, causing scarring over these tissues which directly impacts range of motion and can cause discomfort. This fibrin also takes up room that new, healthy tissue could potentially be regenerating in. Serrapeptase works by helping the body to break down excess scar tissue, enhancing recovery and promoting the healing process.


Saturday, March 18, 2017

Everything You Ever Wanted to Know about Digestive Enzymes

 

 

Everything You Ever Wanted to Know about Digestive Enzymes

Digestive enzymes. We’re betting you’ve heard of them, have a vague idea that they’re good, and wonder if you should be taking them. But this is one area where we also see a lot of confusion. Supplementation of any sort without knowing what or why you’re doing what you’re doing can be just as detrimental to your health as doing nothing at all. So before you stock up on papain and bromelaine, let’s get the complete low-down on all things digestive enzymes from today’s guest expert, Dr. Tim Gerstmar of Aspire Natural Health.

What are digestive enzymes, and why are they so important?

We eat food, but our digestive system doesn’t absorb food, it absorbs nutrients.  Food has to be broken down from things like steak and broccoli into its nutrient pieces: amino acids (from proteins), fatty acids and cholesterol (from fats), and simple sugars (from carbohydrates), as well as vitamins, minerals, and a variety of other plant and animal compounds. Digestive enzymes, primarily produced* in the pancreas and small intestine, break down our food into nutrients so that our bodies can absorb them.
*They’re also made in saliva glands and stomach, but we’re not going to focus on those here.
If we don’t have enough digestive enzymes, we can’t break down our food—which means even though we’re eating well, we aren’t absorbing all that good nutrition.

What would cause digestive enzymes to stop working correctly in the body?

First, diseases may prevent proper digestive enzyme production.
  • Pancreatic problems, including cystic fibrosis, pancreatic cancer, and acute or chronic pancreatitis.
  • Brush border dysfunction, the most severe is long standing Celiac disease, where the brush border is flattened or destroyed. Other diseases like Crohn’s can also cause severe problems.
But even in the absence of any obvious disease, things still may not be working properly.
  • Low-grade inflammation in the digestive tract (such as that caused by “food allergies,” intestinal permeability, dysbiosis, parasitic infection, etc.) can lead to deficiencies in digestive enzymes.
  • Aging has been associated with decreased digestive function, though I personally wonder if this is a result of aging, or aging badly.
  • Low stomach acid—we’ll talk about this more in a future article, but if you have low stomach acid, it’s likely that you won’t have adequate digestive enzymes either.
  • Chronic stress. This is the most common reason for digestive enzyme problems. Our body has two modes: sympathetic “fight or flight,” and parasympathetic “rest and digest.” When we’re in “fight or flight” mode, digestive is given a very low priority, which means digestive function (including digestive enzyme output) is dialed down.  Chronic stress= constant “fight of flight” mode = impaired digestive enzyme output.
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How do we correct a digestive enzyme deficiency?

First, a Whole30 or a Paleo-style diet can help to restore normal digestive function, including digestive enzymes.  Dietary interventions work by reducing inflammation in the body and the digestive tract, improving nutrient deficiencies, removing enzyme inhibitors by taking out things like grains and legumes, and fixing gut bacteria.
However, just because you eat Good Food doesn’t automatically mean your digestion will be healthy. In my previous article, I talked about gut bacteria, which may not be in perfect balance with a Paleo diet alone. Improper digestion is another issue that diet alone may not solve.
Managing chronic stress is vitally important to restoring healthy digestive function. Most of us are cramming food in our faces at our desks or while we’re on the go, then we’re off to do the next thing on our list. We live most of our lives in sympathetic mode—and aren’t giving a high priority to properly digesting our food. When we sit down to eat food, we should switch into a parasympathetic mode, and ideally stay in parasympathetic mode for a while afterwards. Think long European meals, followed by a siesta. (Refer to pages 182-185 in It Starts With Food for more specifics.)
Finally, after implementing these healthy dietary and lifestyle practices, digestive enzyme supplementation may be necessary to help your body properly break down your food.

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http://whole9life.com/2012/09/digestive-enzymes-101/

Monday, March 13, 2017

Everything You Learned About Enzymes Was Wrong. By William Wong N.D., PhD



Everything You Learned About Enzymes Was Wrong.
By William Wong N.D., PhD., Member World Sports Medicine Hall of Fame



Think you know all about nutrition?  OK, name the primary functions of proteolytic (protein eating) enzymes in the body?  If you said digestion go to the rear of the class!  Digestion is one of the last things a proteolytic enzyme does.  While most of us can name the actions of every vitamin and herb in creation, 99% of the people in the natural health, pharmaceutical and even medical world don't know what enzymes really are, what they do, and how they are being used to help human function. 
First let’s talk about what an enzyme is: an enzyme is a large protein molecule that cleaves, cuts or eats specific pre-designated things (think of Pac Man with shark like teeth).   Depending on the programming of the “teeth”, the enzymes fit over certain substances in a lock and key fashion, cutting through one specific type of thing, a particular type of protein let’s say yet leaving undisturbed protein of a similar but slightly different type.  
Enzymes are essential as “bio catalysts”, in other words they speed the action of chemical reactions.  Without enzymes involved in every cellular event in out bodies the chemical reactions within us would be so slow as to make life as we know it impossible.  There are some 3000+ enzymes in the human body, most of them of the proteolytic type. These 3000+ enzymes create between 7000 to 25000 different enzyme reactions.    The 3000 enzymes themselves are created as a result of either our own enzyme production (which is finite in nature), or from ingesting enzymes from our live or uncooked food. 
This leads us to two issues:
1) Enzymes are heat sensitive.  Temperatures of 105 to 125 degrees F kill enzymes and their related activity.  So cooked foods have virtually nothing in the way of enzymes. Enzymes cultured in laboratories can be made with an increased resistance to heat both in terms of degrees and in terms of time exposed to higher temps but overall the enzymes in food die from cooking.
2) Many scientists and physicians in the US still believe that enzymes are too big to pass through the intestinal tract and get into the blood stream intact.  Something the size of Pac Man when compared to the dots he eats cannot possibly be absorbed through the tiny pores of the intestinal membrane.  This ignores the medically known fact that Salmonella, a molecule 5 times larger than the largest enzyme, easily passes through the intestinal wall to be absorbed whole, (i.e. without being broken down and digested), into the blood stream.  For those late bloomers here in the States – there are over 200 peer reviewed medical and university studies proving beyond the shadow of a doubt not only the absorption of enzymes but also their medical therapeutic actions.
By now you may be asking yourself just what do enzymes do?  Let's take a look at the three major forms of basic enzymes in the body and look into the work they do.  There are three major subdivisions of enzymes in the human system:
Proteases, which eat or breakdown protein.
Lipases, which eat or break down fats.
Amylases, which eat or breakdown carbohydrates. 
“Wait a minute”, you'll say, “that all sounds like digestion I though you said that digestion is the last thing an enzymes does”?  Quite so lets look at what these enzymes are cleaving and where! 
Of the 3 enzymes listed, proteases and lipase's have systemic functions: that means they perform jobs all over the body in most every system.  Only amylase, the carbohydrate lysing (cleaving or eating) enzyme acts almost solely in digestion. 
The first thing the proteolytic enzymes do is to create what is known as the enzyme cascade.  Most of the enzymes active in the reactions that occur body wide are proteolytic in nature, that is they are concerned with cleaving a type of specific protein or another (we have literally hundreds of different types and arrangements of proteins in our bodies).    So the vast majority of the 7000 to 25,000 enzymic reactions that need to happen within us are proteolytic in nature.   Aside from the 25,000 possible reactions of protein eating enzymes science now knows they have 5 primary functions:

Natural Anti-Inflammatory.
They are the first line of defense against inflammation. (1,2,3).  Inflammation is a reaction by the immune system to an irritation.  Let’s say you have an injured right knee.  The immune system sensing the irritation the knee is undergoing creates a protein chain called a Circulating Immune Complex (CIC for short), tagged specifically for that right knee.  (The Nobel Prize in biology was won in 1999 by a scientist who found the tagging mechanism).  This CIC floats down to the right knee and causes pain, redness and swelling – the classic earmarks for inflammation.  This at first is a beneficial reaction; it warns us that a part of ourselves is hurt and needs attention.  But, inflammation is self-perpetuating, itself creating an irritation that the body makes CIC’s to in response! 
Aspirin, Ibuprofen, Celebrex, Vioxx and the rest of the Non Steroidal Anti Inflammatory Drugs all work by keeping the body from making all CIC’s.  This ignores the fact that some CIC’s are vital to life, like those that maintain the lining of the intestine and those that keep the kidneys functioning!  Not to mention the fact that they along with acetaminophen are highly toxic to the liver.  Every year 20,000 Americans die from these over the counter drugs and another 100,000 will wind up in the hospital with liver damage, kidney damage or bleeding intestines from the side effects of these drugs. (4,5).
Systemic enzymes on the other hand are perfectly safe and free of dangerous side effects.  They have no LD-50, or toxic dose. (6).  Best of all systemic enzymes can tell the difference between the good CIC’s and the bad ones because hydrolytic enzymes are lock and key mechanisms and their “teeth” will only fit over the bad CIC’s.  So instead of preventing the creation of all CIC’s, systemic enzymes just “eat” the bad ones and in so doing lower inflammation everywhere and with that pain is lowered also.
Anti Fibrosis.
Enzymes eat scar tissue and fibrosis. (7).  Fibrosis is scar tissue and most doctors learn in anatomy that it is fibrosis that eventually kills us all.  Let me explain.  As we age, which starts at 27, we have a diminishing of the bodies’ output of enzymes.  This is because we make a finite amount of enzymes in a lifetime and we use up a good deal of them by the time we are 27.  At that point the body knows that if it keeps up that rate of consumption we’ll run plum out of enzymes and be stone cold dead by the time we reach our 40’s.  (Cystic Fibrosis patients who have virtually no enzyme production to speak of, even as children usually don’t make it past their 20’s before they die of the restriction and shrinkage in the lungs from the formation of fibrosis or scar tissue).  
So our body in its wisdom begins to dole out our enzymes with an eyedropper instead of with a tablespoon; result - the repair mechanism of the body goes off balance and has nothing to reduce the over abundance of fibrin it deposits in nearly every thing from simple cuts, to the inside of our internal organs and blood vessels.  It is then when most women begin to develop things like fibrocystic breast disease, uterine fibroids, endometriosis, and we all grow arterial sclerotic (meaning scar tissue) plaque, and have fibrin begin to spider web its way inside of our internal organs reducing their size and function over time.  This is why as we age our wounds heal with thicker, less pliable, weaker and very visible scars. 
If we replace the lost enzymes we can control and reduce the amount of scar tissue and fibrosis our bodies have.  As physicians in the US are now discovering, even old scar tissue can be “eaten away” from surgical wounds, pulmonary fibrosis, and kidney fibrosis even keloid years after their formation.  Medical doctors in Europe and Asia have known this and used orally administered enzymes for such for over 40 years!   
Blood Cleansing.
The blood is not only the river of life; it is also the river through which the cells and organs dispose of their garbage and dead material.  Enzymes improve circulation by eating the excess fibrin that causes blood to sometimes get as thick as ketchup or yogurt creating the perfect environment for the formation of clots. All of this material is supposed to be cleaned off by the liver on “first pass” or the first time it goes through but given the sluggish and near toxic or toxic states of everyone’s liver these days that seldom happens.  So the sludge remains in the blood waiting for the liver to have enough free working space and enough enzymes to clean the trash out of the blood.  This can take days, in some folk’s weeks!  (8). When systemic enzymes are taken they stand ready in the blood and take the strain off of the liver by; Cleaning excess fibrin from the blood and reducing the stickiness of blood cells.  These two actions minimize the leading causes of stroke and heart attack causing blood clots. (8).Breaking dead material down small enough that it can immediately pass into the bowel. (8).Cleanse the FC receptors on the white blood cells improving their function and availability to fight off infection.  (9).
And here we come to the only warning we have to give concerning the use of   systemic enzyme – don’t use the product if you are a hemophiliac or are on prescription blood thinners like Coumaden, heparin and Plavix.   The enzymes cause the drugs to work better so there is the possibility of thinning the blood too much. 
Immune System Modulating.
Enzymes are adaptogenic seeking to restore a steady state to the body. (9).    When the immune system is running low we become susceptible to infectious disease, when it’s cranked up too high then the system creates antibodies that attack it’s own tissues as are seen in the auto immune diseases of MS, Rheumatoid Arthritis, and Lupus.  Here therapeutic dosing of oral administered systemic enzymes will tone down immune function and eat away at the antibodies the immune system is making to attack its bodies own tissue.
When the immune system is run down too low the enzymes increase immune response, producing more Natural Killer cells, and improving the efficiency of the white blood cells, all leading to improved immunity. 

Virus Fighting.

Viruses harm us by replicating in our bodies.  To do this a virus must bond itself to the DNA in our cells through the medium of its exterior protein cell wall.  Anything that disrupts that cell wall inhibits the ability of that virus viral replication by rendering individual viruses inert. (10,11). Systemic enzymes can tell the difference between the proteins that are supposed to be in your body and those that are foreign or not supposed to be there, (again the enzyme lock and key mechanism).    Even now the US Military has developed a proteolytic enzyme blend to be used as an anti biological warfare agent against Anthrax and viruses. (12). 
As can be seen the primary actions of proteolytic actions are impressive and hold great promise for health and medical applications.
Though the bulk of body wide enzyme reactions are proteolytic the remaining systemic enzyme, lipase performs some important jobs as well.  The most important action of lipase lends itself to service in a few different areas:
Fat Loss / Energy Releasing By Dissolving Body Fat:
Lipase breaks down body fat so that it can start the long drawn out process of becoming blood sugar.   Unfortunately as we age our own production of enzymes decreases and with that our ability to turn fat into energy decreases also.   This could be one of the reasons why it is so difficult to lose weight after 35.   Lipase supplementation could be used to cause the breakdown of body fat and help its conversion into energy, while decreasing body weight and cholesterol. (13).
Still think enzymes are used only for digestion?  Stick around; there are a myriad of other uses and applications for systemic enzymes that will come to the fore in the near future.   Enzymes are our most important nutrients! 
References:
1)  Bodhankar S.L., Et Al: Anti Inflammatory and Analgesic activity of Exclzyme-EN.  Scientific Abstracts, 54th Indian Pharmaceutical Congress 2002, Pune.
2) Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic                   inflammation of otorhinolaryngology pathology: a multicentre, double blind,       randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
3)  Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment of breast       engorgement with Serrapeptase: a randomized double blind controlled trial.       Singapore Med J. 1989:30(l):48-54.

4) Celebrex article Wall Street Journal 19 April 1999. 
 
5) No author listed: Regular Use of Pain Relievers Can Have Dangerous Results.      Kaleidoscope Interactive News, American Medical Association media briefing.      July 24, 1997.
6) Enzymes – A Drug of the Future, Prof. Heinrich Wrba MD and Otto Pecher      MD.  Published 1993 Eco Med.
7) Kakinumu A. et al.: Regression of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.

8) Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology.  Klin Wschr. 65 (1987), 994.
9)  Kunze R., Ransberger K., et at: Humoral immunomodulatory capasity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991.
10) Jager H.: Hydrolytic Enzymes in the therapy of HIV disease.  Zeitschr. Allgemeinmed., 19 (1990), 160.
  • Bartsch W.: The treatment of herpes zoster using proteolytic enzymes.  Der         Informierte Arzt. 2 (1974), 424-429.


Sunday, March 12, 2017

Enzymes to Fight Inflammation?



Enzymes to Fight Inflammation?

 I’ve recently read about the benefits of taking systemic enzyme supplements. The claims are that they fight inflammation and viruses, prevent blood clots, modulate the immune system, and cleanse the blood. What are your thoughts on these supplements? 


Enzymes are specialized protein molecules that catalyze (speed up) biochemical reactions. They are involved in all aspects of metabolism, growth and development, but there is generally no point in taking them as supplements.

The reason is simple:
Enzymes that are ingested are simply broken down in the stomach and small intestine and digested like any other proteins. The only exceptions are the digestive enzymes made by the stomach and pancreas, which work in the gastrointestinal tract, and I occasionally recommend digestive enzyme supplements to patients who have digestive problems. However, the pointlessness of taking systemic enzymes orally hasn’t stopped promoters of systemic enzyme therapy from making many claims about the benefits of their products. Perhaps the best known of these is serratiopeptidase, an enzyme found in silkworm intestines that allows the emerging moth to dissolve its cocoon.

Serratiopeptidase does appear to have anti-inflammatory properties, and it is being promoted online and elsewhere as a treatment for pain associated with arthritis, surgery, trauma and fibromyalgia. It is also is advertised as a treatment for atherosclerotic plaque, the buildup of cholesterol, fat, and calcium in arteries. The claim is that serratiopeptidase “digests” the substances that cause plaque without harming underlying tissue. Most of the published research on serratiopeptidase focuses on its anti-inflammatory properties and, most recently, its potential as a substitute for non-steroidal anti-inflammatory drugs and as a topical treatment for inflammation. However, in February of 2011 a Japanese drug company voluntarily recalled its product generically called serrapeptase because double-blind studies comparing this agent to placebo showed no significant differences between the two. On the market since 1968, the drug was advertised as an effective treatment for conditions ranging from chronic bronchitis to sprained ankles.

Systemic enzyme therapy is also promoted for cancer treatment. Here, proponents claim that certain enzymes remove a protective coating from cancer cells, allowing white blood cells to identify and attack them. According to the American Cancer Society, no scientific evidence exists to support this claim and no well-designed studies have shown that enzyme supplements are effective in treating cancer.  
Andrew Weil, M.D.

Saturday, March 11, 2017

Serracor-NK 300 Capsules Circulatory & Inflammation Support



Serracor-NK -Systemic Enzyme Blend

Understanding Fibrin & Systemic Enzymes

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Fibrin is an insoluble protein the body produces in response to injury or trauma. It is the body’s natural response to recovery.  Fibrin performs important functions in the body.  Although fibrin has many functions, the most important include clotting and wound healing. One of the first steps to wound healing is the process of blood clotting.  The protein precursor fibrinogen is converted into fibrin, which forms a layer of connective tissue inside the damaged blood vessel.  This is a normal process.  To do this, the fibrin strands assemble into a net-like structure over the damaged vessel and harden, forming a “patch” or small clot to prevent further damage.  While fibrin is meant to work as a protective function, too much fibrin build up can cause problems such as:
  • A high level of circulating fibrin in the blood has the potential to accelerate scarring
  • Impede normal circulation
  • more serious fibrotic conditions or cardiovascular conditions
The human body produces enzymes responsible to support all biological reactions within the body. The different systems in our bodies including our cardiovascular, digestive, and immune systems, would not be able to function without the support of these proteolytic enzymes. Enzymes carry out chemical reactions necessary for simple everyday functions such as our metabolism, breathing, and even our heart rate. It is important for us to supplement with necessary enzymes when our bodies fail to supply adequately.
As we age, our bodies gradually become unable to meet the daily demand of producing enzymes. When this occurs, it is imperative for us to begin to supplement our body with the necessary enzymes to prevent havoc within. With the use of proteolytic systemic enzymes, they can increase the support of many conditions including:
  • cardiovascular and respiratory health*
  • the breakdown of excess fibrin*
  • promote faster recovery *
  • immune system regulation*
  • healthy blood sugar levels*

Serracor-NK for Circulatory Support*

Serracor-NK is a powerful blend of antioxidant herbs, CoEnzyme q10 and magnesium with enteric-coated nattokinase and serrapeptase.  These two systemic enzymes have been studied for their fibrinolytic properties. This complete array of proteolytic enzymes, herbs, and minerals supports healthy circulatory and respiratory systems and normal fibrin metabolism.*
Enteric-coated nattokinase and serrapeptase, make Serracor-NK a unique blend. Most nattokinase and serrapeptase brands on the market are not enteric coated, which means they can lose a significant portion of their fibrinolytic activity and effectiveness in the acidic environment of the stomach. The enteric coating of our blend allows these sensitive enzymes to survive the acidic conditions of the stomach, thus allowing them to pass into the circulatory system maintaining high activity levels.

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Key Ingredients in Serracor-NK

  • Enteric-Coated Nattokinase: A powerful fibrinolytic agent, known to support circulatory health.*
  • Enteric-Coated Serrapeptase: known to support the body in fibrinolytic breakdown.*
  • Bromelain: Proteolytic enzyme found in the pineapple plant; known for immune support.*
  • Papain: Derived from papaya, supports the body’s natural immune response.*
  • Lipase: Supports the break-down of fats into essential fatty acids that are needed for healthy circulation.*
  • Rutin: Bioflavonoid that provides antioxidant support.*
  • Amla: Natural source of Vitamin C, supports regulatory immune response.*
  • COENZYME Q10: An essential enzyme and cofactor in metabolism.*
  • Magnesium: An essential mineral used as a cofactor; support cardiovascular and nerve health.*
Serracor-NK supports fibrin levels in the circulatory system.*  In addition, the entire systemic enzyme blend is manufactured in a ISO 9001:2000 and GMP certified facility.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Digest-GI Digestive Enzymes Support 90 Capsules


Digest-GI Complete Digestion

Good Health Begins With Proper Digestion Specialized cells in the pancreas, stomach and salivary glands produce digestive enzymes. These enzymes, along with those found in live foods, facilitate the break-down of food that results in their absorption and the eventual production of energy. When we eat a meal, producing digestive enzymes becomes a high priority for the body, requiring a lot of energy and adding stress to the pancreas. Despite this effort, digestive enzyme needs may still not meet the demands of the body, and undigested food particles may remain. These particles can accumulate and prevent proper nutrient absorption, cause digestive discomfort, or worse, leak back into the bloodstream from the colon and cause toxicity.

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There are a many causes of indigestion and other digestive disorders.  At least 10% of the population is lactose intolerant. Combine this with non-digestible complex sugars from legumes, cruciferous vegetables and cereal grains, abdominal discomfort, bloating and gas are inevitable.  Others consume far more protein than their body’s enzymes can digest, resulting in digestive discomfort. Typically, people reach for an antacid, which only neutralizes stomach acid and slows the digestive process. Yet, the true cause for indigestion has not been addressed. Digestive enzyme supplementation can enhance nutrient absorption, relieve digestive discomfort and promote overall better health.

Digest-GI (DigeSEB-GI) is a premium, all-encompassing blend of digestive enzymes formulated to optimize digestion of dairy, legumes, cruciferous vegetables, cereal grains, proteins and other foods. Digest-GI (DigeSEB-GI) includesalpha and beta amylase, invertase, maltase, alpha galactosidase, lipase, cellulase and a complete array of protease enzymes, all of which are designed to enhance the digestion of carbohydrates, proteins and fats, while increasing the nutritional value of food and reducing the discomforts of incomplete digestion.
Digest-GI (DigeSEB-GI) contains all-natural digestive enzymes specifically tailored to break down a broad range of foods into nutrients that your body can readily use. The powerful combination of proteases in Digest-GI helps hydrolyze proteins into smaller peptides and amino acids. Further, these enzymes are designed to be effective across a wide pH range throughout the entire digestive tract.

After about the age of two years, the body begins to produce less lactase. Undigested lactose molecules pass into the colon and are fermented by bacteria, contributing to bloating, cramping and gas. DigeSEB-GI supports the digestion of lactose, as well as casein and other proteins and fats inherent in dairy products.
Digest-GI (DigeSEB-GI) is also formulated to assist in the breakdown of carbohydrates found in vegetables, grains and legumes. Complex carbohydrates found in these foods are very nutrient dense but slow to digest. Undigested food is fermented in the colon, which can cause discomfort and limit the amount of nutrients made available for the body to absorb. The inclusion of two kinds of amylase in Digest-GI helps breakdown carbohydrates and assimilates them into usable sugars and starches. The complete digestion formula also contains HemiSEB®, a special enzyme complex that breaks down hard-to-digest components of plant fiber. Alpha-galactosidase breaks down complex carbohydrates found in legumes, vegetables, and grains, while reducing the discomforts of incomplete digestion.*


Digest-GI Dosage
Take 1 or more capsules with each meal, or as directed by your healthcare professional.


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